A study of the effectiveness of high-frequency left prefrontal cortex transcranial magnetic stimulat

Por: Estimulação Magnética Transcraniana repetitiva (EMTr)  18/10/2009
Palavras-chave: Depressão, Tratamento Dos Transtornos De Humor, Antidepressivo

 A study of the effectiveness of high-frequency left prefrontal cortex transcranial magnetic stimulation in major depression in patients who have not responded to right-sided stimulation. Fitzgerald PB, McQueen S, Herring S, Hoy K, Segrave R, Kulkarni J, Daskalakis ZJ. Psychiatry Res. 2009 Aug 30;169(1):12-5.The objective of this study was to explore the response rate to high-frequency left-sided repetitive transcranial magnetic stimulation (rTMS) in patients who had failed to respond to right-sided low-frequency stimulation, and to investigate whether there was differential efficacy between stimulation at 5 or 10 Hz. Data from two randomized controlled trials were pooled. In both studies a group of patients were randomized to receive either 5- or 10-Hz left prefrontal rTMS after failing to respond to right-sided stimulation. These patients received blinded 5- or 10-Hz stimulation (but without a sham control) for a period of up to 4 weeks and outcomes were compared. There was a small but significant overall response to left-sided rTMS but no difference in response between the 5- and 10-Hz treatment conditions.

Palavras-chave: Antidepressivo, Clínica de Estimulação Magnética, Depressão, Efeito terapêutico, Eletroconvulsoterapia, Tratamento Dos Transtornos De Humor,

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