EMTr e esquizofrenia: Repetitive transcranial magnetic stimulation for refractory symptoms in schizophrenia.
Repetitive transcranial magnetic stimulation for refractory symptoms in schizophrenia.
PURPOSE OF REVIEW: Schizophrenia is an illness associated with a substantial degree of treatment resistance and suboptimal therapeutic response. In recent years, novel brain stimulation technologies have been identified as potential treatments for schizophrenia and related disorders. Several published studies have assessed the use of repetitive transcranial magnetic stimulation (rTMS) in patients with schizophrenia. RECENT FINDINGS: Most published studies have focused on the use of low-frequency rTMS to treat refractory auditory hallucinations. These studies support the efficacy of stimulation over the temporoparietal cortex. Several other studies have assessed high-frequency stimulation of the prefrontal cortex in the treatment of negative symptoms. Novel protocols to treat auditory hallucinations have been piloted and case reports are emerging on the use of maintenance rTMS to treat auditory hallucinations.
Blumberger DM, Fitzgerald PB, Mulsant BH, Daskalakis ZJ. aDepartment of Psychiatry, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada bDepartment of Psychological Medicine, Monash Alfred Psychiatry Research Centre, The Alfred and Monash University, Victoria, Australia.